In the 14th century, William of Baskerville (Sean Connery), a renowned Franciscan monk, and his apprentice, Adso of Melk (Christian Slater), travel to an abbey where a suspicious death has occurred. Using his deductive powers, William begins investigating what he believes to be murder. During the course of his investigation, several more monks wind up dead. With fear running through the abbey, the church leaders call forth Bernardo Gui (F. Murray Abraham), William's nemesis, to find the truth.